Caloric Restriction and intermittent fasting have also been proven to directly inhibit the mTOR pathway, thereby relieving the inhibition of the autophagy pathway to lead to apoptosis. Conversely, intermittent fasting has long been shown to activate AMPK, which inhibits mTOR from halting autophagy in speedily rising cancer cells. Lastly, https://directivepublications.org/world-journal-of-clinical-cancer-research/